CD56 (123C3.D5), MMab
For In Vitro Diagnostic Use
Description
CD56 or Neural-Cell Adhesion Molecule (NCAM) is a homophilic binding glycoprotein expressed on the surface of neurons, glia and skeletal muscle. CD56 has been implicated in cell-cell adhesion, neurite outgrowth, synaptic plasticity, and learning and memory. Normal cells that stain positively for CD56 antibody include NK cells, activated T-cells, brain and cerebellum, and neuroendocrine tissues. Tumors that are CD56 positive are Myeloma, Myeloid Leukemia, Neuroendocrine tumors, Wilm’s Tumor, Adult Neuroblastoma, NK/T cell Lymphomas, Pancreatic Acinar-cell Carcinoma, Pheochromocytoma, and Small-cell Lung Carcinoma. It is also expressed on some mesodermally-derived tumors (Rhabdomyosarcoma). Ewing’s Sarcoma/PNET is CD56 negative.
Synonymes
CD56, NCAM1, Neural cell adhesion molecule 1, anti-NCAM, anti NCAM, anti-NCAM1, anti NCAM1, anti-CD56, anti CD56, anti-neural cell adhesion molecule 1, anti neural cell adhesion molecule 1, antigen recognized by monoclonal antibody 5 1H11, MSK39, N CAM 1, NCAM, NCAM 1, neural cell adhesion molecule NCAM
Caractéristiques
- Type
- Mouse Monoclonal
- Clone
- 123C3.D5
- Isotype
- IgG1/K
- Réactivité
- Paraffin, Frozen
- Localisation
- Membranous
- Contrôle
- Pancreas, Tonsil, Neuroblastoma, Brain, Thyroid, Prostate, Colon, Lung SCC
- Usage prévu
- For In Vitro Diagnostic Use
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