CD5 (RM314), RMab
For In Vitro Diagnostic Use
Description
CD5 is a glycoprotein monomer with an MW of 67 kDa belonging to the scavenger receptor cysteine-rich (SRCR) family of extracellular domain-like structures. It possesses a large cytoplasmic domain suitable for signal transduction. CD5 antibody is a T-cell marker that also reacts with a range of neoplastic B-cells, e.g., B-cell Chronic Lymphocytic Leukemia (B-CLL), B-cell Small Lymphocytic Lymphoma (BSLL), and Mantle Cell Lymphoma. CD5 antibody expression is found in T-lymphocyte subsets and is modulated during cellular activation; however, it does not react with granulocytes or monocytes.
Synonymes
CD5, anti-cd5, anti cd5, CD5 antigen p56 62, CD5 molecule, LEU1, Lymphocyte antigen T1 Leu 1, T cell surface glycoprotein CD5, T1
Caractéristiques
- Type
- Rabbit Monoclonal
- Clone
- RM314
- Isotype
- IgG
- Réactivité
- Paraffin, Frozen
- Localisation
- Membranous
- Contrôle
- Tonsil, Lymph Node, Spleen, Thymus
- Usage prévu
- For In Vitro Diagnostic Use
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