BIO SB CD45RO (UCHL-1), MMab
For In Vitro Diagnostic Use
Description
The CD45 family consists of multiple members that are all products of a single complex gene. Three isoforms of CD45 exist: on B-lymphocytes, where the protein is called B220 (its molecular mass is 220 kDA); on naive T-lymphocytes, where it is called CD45 RA, and on activated and memory T-lymphocytes, where it is called CD45 RO. CD45RO is a single-chain, transmembraneous glycoprotein which represents the low molecular weight isoform of the Leukocyte Common Antigen (LCA). It is expressed on most thymocytes, about 45% of peripheral blood T-cells, virtually all T-cells in skin reactive infiltrates, and the majority of T-cell malignancies. It is also found on a subset of B-cells and on exceptional B-cell Lymphomas. CD45RO Antibody (T-Cell, Pan) reacts with thymocytes and activated T-cells, but only on a subpopulation of resting T-cells. This antibody shows no reactivity with B-cells, making it a good marker for T-cell tumors to be phenotyped. In addition, granulocytes and monocytes are also labeled with this antibody. T-Cell, Pan has been designated as CD45RO at The International Leukocyte Typing Workshop.
Synonymes
CD45, PTPRC, protein tyrosine phosphatase receptor type C, sc1183, sc-1183, 1183, anti-CD45RO, anti CD45RO, anti-CD45, anti CD45, anti-PTPRC, anti PTPRC, anti-protein tyrosine phosphatase receptor type C, anti protein tyrosine phosphatase receptor type C, Leukocyte common antigen precursor, L CA, Lymphocyte antigen 5, Ly 5, T200, CD45 antigen, B220, CD45R, Lyt 4, loc, GP180, LCA, Leukocyte common antigen, LY5, protein tyrosine phosphatase receptor type c polypeptide, T200 glycoprotein, T200 leukocyte common antigen, receptor type tyrosine protein phosphatase C
Caractéristiques
- Type
- Mouse Monoclonal
- Clone
- UCHL-1
- Isotype
- IgG2a/K
- Réactivité
- Paraffin, Frozen
- Localisation
- Membranous
- Contrôle
- Tonsil, Lymph Node
- Usage prévu
- For In Vitro Diagnostic Use
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