BIO SB CD41 / Integrin alpha IIb (EP178), RMab
For In Vitro Diagnostic Use
Description
ITGA2B encodes CD41, or integrin alpha IIb. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain IIb undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibrinogen receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface medicated signalling. CD41 antibody expression has been found on platelets, megakaryocyes, and immature hematopoietic progenitors.
Synonymes
GP2B, GPalpha IIb, ITGA2B, sc365938, Integrin αIIb, Integrin alphaIIb, Integrin α IIb, anti-Integrin αIIb, anti Integrin αIIb, Integrin alpha-IIb, anti-GP2B, anti GP2B, anti-ITGA2B, anti ITGA2B, anti-GPalpha IIb, anti GPalpha IIb, anti-Integrin alpha-IIb, anti Integrin alpha-IIb, BDPLT2, CD41, anti-cd41, anti cd41, CD41B, GPIIb, GT, GTA, HPA3, Integrin alpha IIb, Integrin alpha IIb heavy chain, Integrin alpha IIb light chain form 1, Integrin alpha IIb light chain form 2, integrin alpha 2b platelet glycoprotein IIb of IIb IIIa complex antigen CD41, platelet fibrinogen receptor alpha subunit, platelet membrane glycoprotein IIb, platelet specific antigen BAK
Caractéristiques
- Type
- Rabbit Monoclonal
- Clone
- EP178
- Isotype
- IgG
- Réactivité
- Paraffin, Frozen
- Localisation
- Membranous, Cytoplasmic
- Contrôle
- Bone Marrow, Spleen
- Usage prévu
- For In Vitro Diagnostic Use
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