Progen Matériel de laboratoire

Description

CD4 is a glycoprotein expressed on the surface of T-helper cells, regulatory T-cells, monocytes, macrophages, and dendritic cells. On T-cells, CD4 is the co-receptor for the T-cell receptor (TCR). It amplifies the signal gener-ated by the TCR by recruiting the tyrosine kinase that is essential for activating many molecules involved in the signaling cascade of an activated T-cell. CD4 antibody expression is involved in the recognition of Type II Major Histocompatability Complex antigens (MHC-II). CD4 is also the receptor for Human Immunodeficiency Virus (HIV). It is present on most T-helper cells and normal thymocytes.

Synonymes

CD4, CD4 molecule, anti-CD4, anti CD4, anti-CD4 molecule, anti CD4 molecule, cluster of differentiation CD4, anti-cluster of differentiation CD4, anti cluster of differentiation CD4, CD4 antigen p55, CD4 receptor, CD4mut, T cell surface antigen T4 Leu 3, T cell surface glycoprotein CD4

Caractéristiques

Type
Rabbit Monoclonal
Clone
RBT-CD4
Isotype
IgG
Réactivité
Paraffin, Frozen
Localisation
Membranous
Contrôle
Tonsil, Lymph Node
Usage prévu
For In Vitro Diagnostic Use

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