BIO SB CD4 (BSB-179), MMab
For In Vitro Diagnostic Use
Description
CD4 is a glycoprotein expressed on the surface of T-helper cells, regulatory T-cells, monocytes, macrophages, and dendritic cells. On T-cells, CD4 is the co-receptor for the T-cell receptor (TCR). It amplifies the signal generated by the TCR by recruiting the tyrosine kinase that is essential for activating many molecules involved in the signaling cascade of an activated T-cell. CD4 antigen is involved in the recognition of Type II Major Histocompatibility Complex antigens (MHC-II). CD4 is also the receptor for Human Immunodeficiency Virus (HIV). It is present on most T-helper cells and normal thymocytes.
Synonymes
CD4, CD4 molecule, anti-CD4, anti CD4, anti-CD4 molecule, anti CD4 molecule, cluster of differentiation CD4, anti-cluster of differentiation CD4, anti cluster of differentiation CD4, CD4 antigen p55, CD4 receptor, CD4mut, T cell surface antigen T4 Leu 3, T cell surface glycoprotein CD4
Caractéristiques
- Type
- Mouse Monoclonal
- Clone
- BSB-179
- Isotype
- IgG2
- Réactivité
- Paraffin, Frozen
- Localisation
- Membranous
- Contrôle
- Tonsil, Lymph Node
- Usage prévu
- For In Vitro Diagnostic Use
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