Progen Matériel de laboratoire

Description

CD38 is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B and natural killer cells. It is a marker of cell activation. The CD38 protein has been linked to HIV infection, Leukemias, Myelomas, solid tumors, Type II Diabetes Mellitus and bone metabolism, as well as some genetically-determined conditions. It has also been used as a prognostic marker in Leukemia. CD38 is highly expressed on thymocytes. It is also expressed by early cells of B and T lineages, NK cells, plasma cells, monocytes and macrophages, and may be detected on cells from Multiple Myeloma, ALL (B and T) and some AML. CD38 antibody expression is useful in subtyping of Lymphomas and Leukemias, inhibition of B-lymphopoiesis, detection of plasma cells, protection of B-cells from apoptosis, and as a marker for activated B and T-cell proliferation.

Synonymes

cADPr hydrolase 1, CD38, anti-CD38, anti CD38, ADPRC 1, Cyclic ADP-ribose hydrolase 1, anti-ADPRC 1, anti ADPRC 1, anti-cADPr hydrolase 1, anti cADPr hydrolase 1, anti-Cyclic ADP-ribose hydrolase 1, anti Cyclic ADP-ribose hydrolase 1, ADP ribosyl cyclase 1, ADP ribosyl cyclase cyclic ADP ribose hydrolase, CD38 antigen p45, CD38 molecule, cyclic ADP ribose hydrolase 1, NAD nucleosidase, T10

Caractéristiques

Type
Rabbit Monoclonal
Clone
EP135
Isotype
IgG
Réactivité
Paraffin, Frozen
Localisation
Membranous
Contrôle
Tonsil, Lymph Node, Breast
Usage prévu
For In Vitro Diagnostic Use

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