BIO SB CD25 (RBT-CD25), RMab
For In Vitro Diagnostic Use
Description
CD25 is the alpha chain of the IL-2 receptor. It is a type I transmembrane protein present on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes that associates with CD122 to form a heterodimer that can act as a high-affinity receptor for IL-2. Studies have shown that a large proportion of resting memory T cells constitutively express CD25. CD25 antibody is expressed in most B-cell neoplasms, some acute nonlymphocytic leukemias, neuroblastomas, and tumor infiltrating lymphocytes. Its soluble form, called sIL-2R may be elevated in these diseases and is occasionally used to track disease progression. CD25 is also utilized in cases of mastocytosis.
Synonymes
IL-2Rα, IL-2Ralpha, IL-2R alpha, IL-2Ra, IL-2R a, IL 2R alpha, sc-19628, 19628, IL 2Rα, IL2Rα, CD25, IDDM10, IL 2 RA, IL2 RA, IL2R, IL2RA, interleukin 2 receptor alpha, p55, TAC antigen, TCGFR, IL 2 receptor subunit alpha, IL 2R subunit alpha, Interleukin 2 receptor subunit alpha, anti-cd25, anti cd25
Caractéristiques
- Type
- Rabbit Monoclonal
- Clone
- RBT-CD25
- Isotype
- IgG
- Réactivité
- Paraffin, Frozen
- Localisation
- Cytoplasmic, Membranous
- Contrôle
- Tonsil, Small Bowel, Spleen, Mastocytosis,Hodgkin’s Lymphoma
- Usage prévu
- For In Vitro Diagnostic Use
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