BIO SB CD23 (1B12), MMab
For In Vitro Diagnostic Use
Description
CD23, also known as Fc epsilon RII, is the “low affinity” receptor for IgE, an antibody isotype involved in allergy and (arguably) resistance to parasites, and is important in regulation of IgE levels. Unlike many of the antibody receptors, CD23 is a C-type lectin. It is found on mature B-cells, activated macrophages, eosinophils, follicular dendritic cells and platelets. CD23 is a B-cell antibody that is useful for differentiating between B-CLL and B-SLL’s that are CD23 positive from Mantle-cell Lymphomas and Small-Cleaved Lymphomas that are CD23 negative. This antibody reacts with the antigen that is found on a subpopulation of peripheral blood cells, B-lymphocytes and on EBV-transformed B-lymphoblastoid cell lines.
Synonymes
Fcer2a, BLAST 2, C type lectin domain family 4 member J, CD23, CD23 antigen, CD23A, CLEC4J, Fc fragment of IgE low affinity II receptor for CD23, fc epsilon RII, FCE2, IGEBF, Immunoglobulin E binding factor, low affinity immunoglobulin epsilon Fc receptor, Low affinity immunoglobulin epsilon Fc receptor membrane bound form, Low affinity immunoglobulin epsilon Fc receptor soluble form, Lymphocyte IgE receptor, cd 23, anti-cd23, anti cd23
Caractéristiques
- Type
- Mouse Monoclonal
- Clone
- 1B12
- Isotype
- IgG
- Réactivité
- Paraffin, Frozen
- Localisation
- Membranous
- Contrôle
- Tonsil, Lymph Node
- Usage prévu
- For In Vitro Diagnostic Use
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