Progen Matériel de laboratoire

Description

CD20 is a transmembrane, non-glycosylated protein expressed on B-cell precursors and mature B-cells, but lost following differentiation into plasma cells. This antibody does not cross-react with non-hematopoietic neoplasms. CD20 (B-cell Pan) reacts with a membrane antigen present in B-cells. CD20 antibody strongly recognizes Reed-Sternberg cells predominant in Hodgkin’s disease. Since no staining of histiocytes or plasma cells has been observed and CD20 antibody has not been detected in T-cell malignancies, it is a very strong marker of B-cell Lymphomas. B-cell Panmarker recognizes a formalin-resistant intracytoplasmic antigen.

Synonymes

S4A1, anti-CD20, anti CD20, B-lymphocyte antigen CD20, Leukocyte surface antigen Leu-16, anti-MS4A1, anti MS4A1, anti-B-lymphocyte antigen CD20, anti B-lymphocyte antigen CD20, anti-Leukocyte surface antigen Leu-16, anti Leukocyte surface antigen Leu-16, membrane spanning 4 domains subfamily A member 1, B1, Bp35, CD20, CVID5, LEU 16, MS4A2, S7

Caractéristiques

Type
Mouse Monoclonal
Clone
L26
Isotype
IgG2a/K
Réactivité
Paraffin, Frozen
Localisation
Membranous
Contrôle
Tonsil, Lymph Node
Usage prévu
For In Vitro Diagnostic Use

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