CD20 (L26), MMab
For In Vitro Diagnostic Use
Description
CD20 is a transmembrane, non-glycosylated protein expressed on B-cell precursors and mature B-cells, but lost following differentiation into plasma cells. This antibody does not cross-react with non-hematopoietic neoplasms. CD20 (B-cell Pan) reacts with a membrane antigen present in B-cells. CD20 antibody strongly recognizes Reed-Sternberg cells predominant in Hodgkin’s disease. Since no staining of histiocytes or plasma cells has been observed and CD20 antibody has not been detected in T-cell malignancies, it is a very strong marker of B-cell Lymphomas. B-cell Panmarker recognizes a formalin-resistant intracytoplasmic antigen.
Synonymes
S4A1, anti-CD20, anti CD20, B-lymphocyte antigen CD20, Leukocyte surface antigen Leu-16, anti-MS4A1, anti MS4A1, anti-B-lymphocyte antigen CD20, anti B-lymphocyte antigen CD20, anti-Leukocyte surface antigen Leu-16, anti Leukocyte surface antigen Leu-16, membrane spanning 4 domains subfamily A member 1, B1, Bp35, CD20, CVID5, LEU 16, MS4A2, S7
Caractéristiques
- Type
- Mouse Monoclonal
- Clone
- L26
- Isotype
- IgG2a/K
- Réactivité
- Paraffin, Frozen
- Localisation
- Membranous
- Contrôle
- Tonsil, Lymph Node
- Usage prévu
- For In Vitro Diagnostic Use
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