BIO SB CD15 (BSB-119), MMab
For In Vitro Diagnostic Use
Description
CD15 is a phosphatidylinositol-anchored transmembrane protein found on neutrophils and which may be involved in phagocytosis. It is expressed in patients with Hodgkin’s Disease, some B-cell Chronic Lymphocytic Leukemias, Acute Lymphoblastic Leukemias, and most Acute Non-Lymphocytic Leukemias. It is also called Lewis x. A positive reaction for CD15 antibody combined with a negative reaction for CD45 and other B and T-lineage markers provides support for Reed-Sternberg cells found in Hodgkin’s disease. Also, this antibody does not detect Mesotheliomas, making it a more frequently used antibody to distinguish Epithelial Mesothelioma from Adenocarcinoma.
Synonymes
FUT4, 3 FAL, alpha 1 3 fucosyltransferase, CD15, ELAM ligand fucosyltransferase, ELAM 1 ligand fucosyltransferase, ELFT, FCT3A, FUC TIV, Fucosyltransferase 4, fucosyltransferase 4 alpha 1 3 fucosyltransferase myeloid specific, Fucosyltransferase IV, fucT IV, FUTIV, Galactoside 3 L fucosyltransferase, Lewis X, LeX, SSEA 1, stage specific embryonic antigen 1, anti-cd15
Caractéristiques
- Type
- Mouse Monoclonal
- Clone
- BSB-119
- Isotype
- IgM
- Réactivité
- Paraffin, Frozen
- Localisation
- Cytoplasmic, Membranous
- Contrôle
- Tonsil, Lymph Node, Hodgkin’s Lymphoma
- Usage prévu
- For In Vitro Diagnostic Use
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