Progen Matériel de laboratoire

Description

CD11c antibody (1TGAX) is a member of the leukointegrin family and shares the same beta subunit with other members of the leukocyte adhesion molecule family, which include CD11a (LFA-1), CD11b (MAC-1), and CD11d (ITGAD), but has a unique alpha chain. CD11c is a type I transmembrane protien found at high levels on most human dendritic cells, but also on monocytes, macrophages, neutrophils, and some B cells that induces cellular activation and helps trigger neutrophil respiratory burst. CD11c antibody is expressed in Hairy Cell leukemias, Acute Nonlymphocytic Leukemias, and some B-cell Chronic Lymphocytic Leukemias.

Synonymes

Cd11c, Integrin αX, Integrin alphaX, Integrin alpha X, Integrin α X, Itgax, anti-Integrin αX, anti Integrin αX, anti-Itgax, anti Itgax, Integrin alpha-X, anti-CD11C, anti CD11C, anti-Integrin alpha-X, anti Integrin alpha-X, AI449405, Cr4, N418, CD11C p150, complement receptor 4, integrin aX

Caractéristiques

Type
Rabbit Monoclonal
Clone
EP157
Isotype
IgG
Réactivité
Paraffin, Frozen
Localisation
Cytoplasmic
Contrôle
Bone Marrow, Spleen, Tonsil, Colon, Hairy Cell Leukemia
Usage prévu
For In Vitro Diagnostic Use

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