BIO SB CD10 (RBT-CD10), RMab
For In Vitro Diagnostic Use
Description
CD10, also known as neutral endopeptidase (NEP), Neprilysin, and common Acute Lymphoblastic Leukemia antigen (CALLA), is a zinc-dependent metalloprotease enzyme that degrades a number of small secreted peptides,most notably the amyloid beta peptide whose abnormal misfolding and aggregation in neural tissue has been implicated as a cause of Alzheimer’s Disease. CD10 is a useful marker for the characterization of childhood Leukemia and B-cell Lymphomas. This antibodyreacts with the antigens of Lymphoblastic, Burkitt’s, and Follicular Lymphomas, and Chronic Myelocytic Leukemia. Also, CD10 detects the antigen of glomerular epithelial cells and the brush border of the proximal tubules. This characteristic may be helpful in interpreting renal ontogenesis, in conjunction with other markers. Other non-lymphoid cells that are reactive with CD10 are breast myoepithelial cells, bile canaliculi, neutrophils, a small population of bone marrow cells, fetal small intestine epithelium, and normal fibroblasts.
Synonymes
atriopeptidase, Enkephalinase, MME, neprilysin, sc46656, sc-46656, 46656, anti-CD10, anti CD10, anti-Neprilysin, anti Neprilysin, anti-MME, anti MME, anti-Atriopeptidase, anti Atriopeptidase, anti-Enkephalinase, anti Enkephalinase, 6030454K05Rik, C85356, CALLA, CD10, common acute lymphoblastic leukemia antigen, membrane metallo endopeptidase, NEP, Neutral endopeptidase, neutral endopeptidase 24 11, Common acute lymphocytic leukemia antigen, DKFZp686O16152, membrane metallo endopeptidase neutral endopeptidase enkephalinase, membrane metallo endopeptidase neutral endopeptidase enkephalinase CALLA CD10, membrane metallo endopeptidase variant 1, membrane metallo endopeptidase variant 2, MGC126681, MGC126707, 2411, SFE, skin fibroblast elastase
Caractéristiques
- Type
- Rabbit Monoclonal
- Clone
- RBT-CD10
- Isotype
- IgG
- Réactivité
- Paraffin, Frozen
- Localisation
- Cytoplasmic, Membranous
- Contrôle
- Kidney, Tonsil, Lymph Node
- Usage prévu
- For In Vitro Diagnostic Use
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