BIO SB c-Myc (EP121), RMab
For In Vitro Diagnostic Use
Description
Oncogene-encoded proteins c-Myc, n-Myc, and l-Myc function in cell proliferation, differentation and neoplastic disease. A mutated version of Myc is found in many cancers, which causes Myc to be constitutively expressed. This leads to the unregulated expression of many genes, some of which are involved in cell proliferation, and result in the formation of cancer. c-Myc is a transcription factor and is a proto-oncogene that is the focal point in cell cycle regulation, metabolism, apoptosis, differentiation, cell adhesion, and tumorigenesis. A common human translocation involving Myc is t(8;14), which is criticial to the development of most cases of Burkitt’s Lymphoma. Malfunctions in Myc have also been found in carcinoma of the cervix, colon, breast, lung, and stomach.
Synonymes
c Myc, MYC, cMyc, sc40, sc-40, 40, anti-c-Myc, anti c-Myc, anti-c Myc, anti-cMyc, anti c Myc, anti cMyc, anti-Myc, anti Myc, avian myelocytomatosis viral oncogene homolog, bHLHe39, Myc proto oncogene protein, transcription factor p64, v myc avian myelocytomatosis viral oncogene homolog, v myc myelocytomatosis viral oncogene homolog avian, class E basic helix loop helix protein 39, MRTL, myc related translation localization regulatory factor, Proto oncogene c Myc, 9E10
Caractéristiques
- Type
- Rabbit Monoclonal
- Clone
- EP121
- Isotype
- IgG
- Réactivité
- Paraffin, Frozen
- Localisation
- Nuclear, Cytoplasmic
- Contrôle
- Burkitt Lymphoma, Lung Cancer, Prostate Cancer
- Usage prévu
- For In Vitro Diagnostic Use
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