BIO SB Beta-Catenin (RM276), RMab
For In Vitro Diagnostic Use
Description
Beta-Catenin is a subunit of the Cadherin protein complex. Cadherins are a type of protein normally expressed on the surface of certain cells. Specifically, Beta-Cateinin is a 92 kDa protein normally found in the cytoplasm of the cell in the sub-membranous location. The Beta-Catenin antibody is associated with E-Cadherin and may be essential for the function of E-Cadherin. Mutations in the Beta-Catenin gene result in the nuclear accumulation of this protein. Nuclear accumulation of this protein has been demonstrated in Fibromatosis lesions of the breast and abdomen, and therefore is useful in differentiating this lesion from other spindle-cell lesions that may occur in these locations.
Synonymes
CTNNB1, sc7963, β-catenin, b-catenin, b catenin, beta catenin, beta-catenin, sc-7963, 7963, β catenin, βcatenin, anti-β-catenin, anti β-catenin, anti-β catenin, anti-βcatenin, anti β catenin, anti βcatenin, anti beta-Catenin, anti CTNNB1, anti-beta-Catenin, anti-CTNNB1, catenin cadherin associated protein beta 1 88kDa, catenin beta 1, CTNNB, DKFZp686D02253, FLJ25606, FLJ37923, betacatenin, bcatenin, catenins, PRO2286
Caractéristiques
- Type
- Rabbit Monoclonal
- Clone
- RM276
- Isotype
- IgG
- Réactivité
- Paraffin, Frozen
- Localisation
- Nuclear, Cytoplasmic, Membranous
- Contrôle
- Fibromatosis of the Breast and Abdomen, Breast, Abdomen, Colon, Testis, Pancreas
- Usage prévu
- For In Vitro Diagnostic Use
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