BIO SB Androgen Receptor (BSB-4), MMab
For In Vitro Diagnostic Use
Description
The androgen receptor (AR) is a type of nuclear receptor which is activated by binding of either of the androgenic hormones testosterone or dihydrotestosterone. The main function of the androgen receptor is as a DNA-binding transcription factor which regulates gene expression. However, the androgen receptor has additional functions independent of DNA binding. The AR signaling pathway plays a key role in development and function of male reproductive organs, including the prostate and epididymis. AR also plays a role in nonreproductive organs, such as muscle, hair follicles, and the brain. Androgen Receptor antibody reacts with the androgen receptor and also with the newly-described A form of the receptor. This antibody does not cross-react with estrogen, progesterone or glucocorticoid receptors. Abnormalities in the AR-signaling pathway have been linked to a number of diseases, including Prostate Cancer, Kennedy’s Disease and male infertility.
Synonymes
anti-androgen receptor, ar antibody, anti-ar, ar ihc, androgen-receptor, anti-androgen-receptor,
Caractéristiques
- Type
- Mouse Monoclonal
- Clone
- BSB-4
- Isotype
- IgG1
- Réactivité
- Paraffin, Frozen
- Localisation
- Nuclear
- Contrôle
- Prostate, Prostatic Adenocarcinoma
- Usage prévu
- For In Vitro Diagnostic Use
Intéressé par ce produit ?
Indiquez la référence et le conditionnement souhaités, nous revenons vers vous rapidement.