BIO SB Alpha-Fetoprotein (BSB-23), MMab
For In Vitro Diagnostic Use
Description
Alpha-fetoprotein (AFP) is a protein which in humans is encoded by the AFP gene. This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. This protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem on chromosome 4. Alpha-Fetoprotein antibody positive staining is seen in hepatocytes of fetal liver and hepatoma. Since only traces of AFP are found in adult serum, elevated levels suggest either a benign or malignant lesion of the liver, a Yolk-Sac Carcinoma, or one of a few other tumors. In conjunction with elevated serum levels, AFP has been immunohistochemically demonstrated in Yolk-Sac Carcinomas in gonadal and extragonadal sites of hepatic malignancies and a few other neoplasms.
Synonymes
anti-alpha fetoprotein, alpha-fetoprotein, af ihc, anti-af, alphafetoprotein, anti-alphafetoprotein, AFP, alpha 1 fetoprotein, anti-AFP, anti AFP, Alpha-fetoglobulin, Alpha-fetoprotein, anti-Alpha 1 Fetoprotein, anti Alpha 1 Fetoprotein, anti-Alpha-fetoglobulin, anti Alpha-fetoglobulin, anti-Alpha-fetoprotein, anti Alpha-fetoprotein, Alpha fetoglobulin, alpha fetoprotein, FETA, HPAFP, alpha fetoprotein precursor
Caractéristiques
- Type
- Mouse Monoclonal
- Clone
- BSB-23
- Isotype
- IgG2a/K
- Réactivité
- Paraffin, Frozen
- Localisation
- Cytoplasmic
- Contrôle
- Fetal Liver, Hepatocellular Carcinoma
- Usage prévu
- For In Vitro Diagnostic Use
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