Albumin (Polyclonal), RPab

Description

The albumins are a family of globular proteins, the most common of which are the serum albumins. Albumins are commonly found in blood plasma and differ from other blood proteins in that they are not glycosylated. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Mutations in this gene on chromosome 4 result in various anomalous proteins. Low albumin antibody expression (hypoalbuminemia) may be caused by liver disease, nephrotic syndrome, burns, protein-losing enteropathy, malabsorption, malnutrition, late pregnancy, artefact, genetic variations and malignancy. High albumin (hyperalbuminemia) is almost always caused by dehydration. In some cases of retinol (Vitamin A) deficiency, the albumin level can be elevated to high-normal values. It has been reported in systemic lupus erythematosus (SLE) patients an increased prevalence of IgG auto-antibodies against human serum albumin (anti-HSA IgG) that are associated with SLE disease activity.

Caractéristiques

Type

Rabbit Polyclonal

Clone

Polyclonal

Isotype

IgG

Réactivité

Paraffin, Frozen

Localisation

Cytoplasmic

Contrôle

Salivary Gland, Kidney, Tonsil, Lupus Erythematosus

Usage prévu

For In Vitro Diagnostic Use. This antibody is intended for use in Immunohistochemical (IHC) and Immunofluorescence (IF) applications on formalin-fixed paraffin-embedded tissues (FFPE), frozen tissue sections and cell preparations. Interpretation of results should be performed by a qualified medical professional.