BIO SB ACTH (BSB-25), MMab
For In Vitro Diagnostic Use
Description
Adrenocorticotropic Hormone (ACTH or corticotropin) is a polypeptide hormone synthesized from POMC, (Pro-opiomelanocortin) and secreted from corticotropes in the anterior lobe of the pituitary gland in response to Corticotropin-releasing Hormone (CRH) released by the hypothalamus. It consists of 39 amino acids. ACTH antibody is a useful marker in the classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs), as well as other tumors (e.g.,some Small-Cell Carcinomas present in lung tissue) causing Paraneoplastic Syndromes by secreting ACTH.
Synonymes
OMC, proopiomelanocortin, ACTH, CLIP, LPH, MSH, NPP, POC, anti-acth, anti acth, adrenocorticotropic hormone, anti-adrenocorticotropic hormone, cotricotropin, anti-corticoptropin
Caractéristiques
- Type
- Mouse Monoclonal
- Clone
- BSB-25
- Isotype
- IgG1/K
- Réactivité
- Paraffin, Frozen
- Localisation
- Cytoplasmic
- Contrôle
- Normal Pituitary
- Usage prévu
- For In Vitro Diagnostic Use
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